Best Spray To Kill Weeds But Not Grass for Lawn Spot Treatment

#1 · Best Overall

1. Ortho WeedClear with Comfort Wand

• Form: Spray
• Weight: 9.4 lb

Best for: Precise lawn spot treatment.

Why it ranks #1: Designed to kill listed weeds without harming grass when used as directed; the Comfort Wand enables precise spraying, and the label lists over 250 weeds.

A continuous-spray Comfort Wand gives Ortho WeedClear precise control without pumping, making it easier to target listed weeds across a lawn. Its lawn-friendly formula is described as targeting common weeds without harming grass when used as directed, and the product lists more than 250 broadleaf weeds, including dandelions and clover.

The no-pump wand supports repeated spot applications without the interruption of manual pumping, while its precise spray control helps direct product onto individual weeds. Ortho says the formula targets more than 250 common broadleaf weeds, including chickweed, clover, poison ivy, and dollarweed, so it covers a broad set of lawn targets. Apply only as directed: avoid use when rain is expected within an hour, and let the spray dry before people or pets enter the treated area.

Skip it if you need a stated rainproof interval; Bonide Chickweed, Clover & Oxalis Killer is described as rainproof after hours of application.

A good fit for lawn owners who want controlled spot application against a wide range of listed broadleaf weeds. Follow the label, avoid imminent rain, and keep people and pets off treated areas until dry.

Listed on Amazon as: Ortho WeedClear Weed Killer for Lawns with Comfort Wand, 1 gal.

#2 · Best Spot Treatment

2. Ortho Weed B Gon

• Form: Spray
• Weight: 1.5 lb

Best for: Trigger-spray broadleaf spot control.

Why it ranks #2: Ready-to-use trigger format suits targeted lawn applications, and the product lists 250-plus weeds with a lawn-safe claim when used as directed.

A ready-to-use trigger format makes Ortho Weed B Gon straightforward for spot-treating listed lawn weeds without mixing. It targets more than 250 weeds, including dandelions and clover, and is described as killing to the root with results in hours while not harming lawns when used as directed.

The RTU trigger applicator supports direct treatment of individual weed patches, avoiding the setup of a hose-end product for small jobs. Ortho lists more than 250 weeds and says the formula kills to the root, with results in hours; dandelions and clover are specifically named. Use only as directed and keep the spray away from desirable plants and bodies of water. The supplied instructions also call for protective clothing and gloves when handling.

Skip it if you want a continuous-spray wand rather than a trigger; Ortho WeedClear Weed Killer for Lawns with Comfort Wand offers no-pump continuous application.

A practical choice for occasional spot treatment of listed broadleaf weeds, especially dandelions and clover, without mixing. It suits small targeted jobs; follow handling directions and keep spray away from desirable plants and water.

Listed on Amazon as: Ortho Weed B Gon Weed Killer, 24oz, RTU Trigger

#3 · Fast Visible Results

3. Spectracide Weed Stop

• Form: Liquid
• Weight: 2.4 lb

Best for: Fast visible lawn results.

Why it ranks #3: Lists control of 460-plus weeds and visible results in three hours; it is for specified lawn grasses, with a 45–90°F application range.

Visible results in three hours are the clearest differentiator of Spectracide Weed Stop for Lawns, which kills listed weeds by contact and targets roots. Its ready-to-spray format treats established lawn types including bluegrass, fescue, zoysia, Bermuda, and perennial ryegrass, making it a targeted option for those grasses.

The ready-to-spray concentrate avoids a separate mixing step, while contact action and root-killing claims address both visible weed growth and roots. Spectracide lists more than 460 weeds, including dandelion, chickweed, clover, and yellow nutsedge, and states results can be visible in three hours. Application has temperature limits: use between 45°F and 90°F, and avoid daytime temperatures above 90°F. Zoysiagrass just emerging from dormancy is also specifically excluded.

Skip it if you need treatment during temperatures above 90°F; Roundup For Lawns3 lists Northern grasses and rainproof performance in three hours.

A fit for lawn owners seeking fast visible results on listed weeds in compatible grass types. Check the temperature window and grass-stage restrictions before spraying, particularly if your lawn is zoysia emerging from dormancy.

Listed on Amazon as: Spectracide Weed Stop For Lawns Concentrate Ready-To-Spray, 32 Oz

#4 · Northern Grass Pick

4. Roundup for Lawns3

• Form: Spray
• Weight: 8 oz

Best for: Northern-grass season-long control.

Why it ranks #4: Specifically targets listed weeds in Northern grasses, including crabgrass and dandelion, and offers ready-to-spray application with rainproofing in three hours.

Up to three months of listed weed control sets Roundup For Lawns3 apart for buyers treating Northern grasses. This ready-to-spray product targets 253 weed types, including crabgrass, dandelion, clover, and yellow nutsedge, and is described as starting immediately and becoming rainproof in three hours.

The ready-to-spray format connects application with a hose-end applicator, avoiding a separate concentrate-mixing step. Its 253-weed coverage includes both broadleaf targets and crabgrass, while the listed up-to-three-month control may reduce the need for repeated treatment within that stated period. The product is specifically for listed Northern grasses, so it is not a general choice for every lawn type. Apply to actively growing weeds; the supplied information notes that multiple applications at 21-day intervals may be required.

Skip it if you have a lawn outside the listed Northern grasses; Spectracide Weed Stop For Lawns lists Bermuda, zoysia, fescue, bluegrass, and perennial ryegrass.

A match for Northern-grass owners seeking broad listed weed coverage and a stated rainproof window. Its grass-type restriction is central to fit, and actively growing weeds are the recommended target for application.

Listed on Amazon as: Roundup for Lawns3 Ready-to-Spray, 32 fl. oz.

#5 · Broadleaf Specialist

5. Bonide Chickweed Clover Oxalis Killer

• Form: Spray
• Weight: 8 lb

Best for: Tough broadleaf weed control.

Why it ranks #5: Targets more than 100 tough-to-control weeds in residential turf and is designed to kill broadleaf weeds to the roots without killing lawn grasses.

Systemic action that kills weeds down to the roots distinguishes Bonide Chickweed, Clover & Oxalis Killer from a surface-only spot spray. Its ready-to-use formula targets more than 100 tough weeds, including chickweed, clover, oxalis, and ground ivy, while the product is intended for residential turf and lawn grasses when used as directed.

Because the spray is ready to use, application does not require mixing; that can simplify treating patches of listed lawn weeds. Bonide describes systemic action down to the roots and says the product begins working overnight, supporting buyers who want more than visible top growth affected. Its weed list includes chickweed, clover, dandelions, ground ivy, and oxalis, among more than 100 weeds. The supplied details also describe it as rainproof after hours of application, so timing still matters.

Skip it if you need an exact rain-free waiting period; Roundup For Lawns3 specifies rainproof performance in three hours.

Choose this for residential turf with difficult broadleaf weeds such as oxalis, chickweed, or ground ivy, especially if root-level action matters. It is ready to use, but the rainproof timing is stated only as hours after application.

Listed on Amazon as: Bonide Chickweed, Clover & Oxalis Killer, 128 oz Ready-to-Use Spray

#6

6. Sunday Dandelion Doom

• Form: Liquid

Best for: Iron-based weed and moss spot treatment.

Why it ranks #6: Uses chelated iron to spot-treat dandelions, moss, algae, and other broadleaf weeds while keeping grass unharmed when used as directed.

Chelated iron (FeHEDTA) gives Sunday Dandelion Doom a specific role: spot-treating tough weeds, moss, algae, and lichen while keeping grass unharmed when used as directed. The two-pack listing and visible results in hours make it a targeted option for buyers addressing more than ordinary broadleaf weeds.

The iron-based formula is described as killing targets down to the roots, while spot-treatment directions help confine application to affected patches rather than treating the whole lawn. Its stated targets extend beyond dandelions and broadleaf weeds to moss, algae, and lichen, which can make it useful for mixed lawn-surface problems. Sunday reports visible results in hours and says to repeat as needed for long-lasting control all season. Avoid application when rain is expected within several hours.

Skip it if you need a precise three-hour rainproof window; Roundup For Lawns3 states that it is rainproof in three hours.

This fits lawn owners spot-treating dandelions alongside moss, algae, or lichen while aiming to preserve grass. Its rain restriction and spot-treatment directions matter; avoid applying if rain is expected within several hours.

Listed on Amazon as: Sunday Dandelion Doom, Iron-Based Weed & Moss Killer, 32oz 2-Pack

#7

7. Ortho WeedClear Ready-to-Use

• Form: Liquid

Best for: Ready-to-use lawn spot spraying.

Why it ranks #7: Ready-to-use spot treatment lists crabgrass, dandelion, clover, and other weeds, with a claim that lawn grasses are unharmed when used as directed.

A ready-to-use Comfort Wand makes Ortho WeedClear Lawn Weed Killer convenient for targeting listed weeds without mixing. It is described as killing more than 200 major broadleaf and grass weeds down to the root, including crabgrass, dandelion, clover, and creeping charlie, while sparing lawn grasses when used as directed.

The ready-to-use format supports direct spot treatment, and the Comfort Wand helps apply product where listed weeds appear rather than preparing a separate mixture. Its weed range includes crabgrass and broadleaf targets such as dandelion, clover, chickweed, and creeping charlie, with the product describing root-level control from one application. Ortho says it can be used on listed lawn grasses, including northern lawn grasses and Bermudagrass; consult the label for the full weed and grass lists.

Skip it if you need a stated rainproof interval for scheduling; Roundup For Lawns3 is listed as rainproof in three hours.

Consider this for targeted lawn treatment when weeds include crabgrass alongside broadleaf types and you want a ready-to-use wand. Confirm the label’s listed grass and weed coverage, since the supplied details do not state a rainproof interval.

Listed on Amazon as: Ortho WeedClear Lawn Weed Killer Ready-to-Use with Comfort Wand, 1 gal.

#8

8. Scotts Liquid Turf Builder Plus 2

• Form: Spray
• Weight: 8 oz

Best for: Hose-end weed control and feeding.

Why it ranks #8: Combines listed weed control with a quick nitrogen boost and hose-end application, but the supplied details give less specific lawn-compatibility information.

A hose-end applicator combines weed control with a quick nitrogen boost, giving Scotts Liquid Turf Builder a lawn-feeding role beyond spot spraying. The 25-0-2 formula is intended to control listed broadleaf weeds while adding fertilizer, making it a fit for buyers treating actively growing lawn weeds and seeking simultaneous nitrogen application.

Connecting the bottle to a garden hose turns application into an even lawn spray rather than requiring a separate fertilizer step, while the 25-0-2 NPK formula supplies the advertised nitrogen boost. The product targets listed broadleaf weeds such as buckhorn and works best when weeds are actively growing. After application, do not water the treated area for 48 hours; the label also notes that some hard-to-control weeds may need another application in three to four weeks.

Skip it if you want a dedicated ready-to-use spot spray without a fertilizer component; Ortho Weed B Gon Weed Killer is an RTU trigger spray.

This suits lawn owners who want to apply listed broadleaf weed control and nitrogen in one hose-end pass. It is less suitable when you cannot keep the treated lawn unwatered for 48 hours or need only isolated spot treatment.

Listed on Amazon as: Scotts Liquid Turf Builder with Plus 2 Weed Control, 32 fl. oz.

#9

9. Natural Elements Weed Killer

• Form: Spray

Best for: Vinegar-based non-lawn weed control.

Why it ranks #9: Its vinegar-derived formula is described as effective on weeds and grasses but explicitly says it will kill grass, so it does not fit lawn-safe spraying.

A vinegar-derived, ready-to-use spray needs no mixing, but Natural Elements Weed Killer is not a grass-safe lawn spray: its instructions say it will kill grass. That makes it a better fit for weeds in rock beds, mulch, or other areas where grass and desirable plants are not the target.

The no-mix formula lets users spray weeds until wet without preparing a solution, which simplifies treatment in appropriate non-lawn areas. The product lists uses around gardens, flowerbeds, landscaping, trees, rock beds, and mulched areas, but also explicitly warns that it kills grass and should not be applied directly to lawns unless grass is meant to be killed. Its vinegar-derived formula is identified as natural; keep the spray away from vegetation you want to preserve.

Skip it if you need to kill weeds within living lawn grass; Ortho WeedClear Weed Killer for Lawns is described as grass-safe when used as directed.

Choose this for weeds in non-lawn spots such as rock beds or mulch where grass can be killed. It is not the right answer for preserving turf, and avoid spraying any desirable plants in its path.

Listed on Amazon as: Natural Elements Weed Killer | Pet Safe, Safe Around Children | Natural Herbicide (1 Gallon)